Antibacterial Mangosteen (Garcinia mangostana Linn.) peel extract encapsulated in Chitosan

Mangosteen peel extract contains xanthone compound having phenol basic structure. Because xanthone is insoluble in water, therefore mangosteen peel extract encapsulated by polymer substance through encapsulation technology is necessity. Mangosteen peel were powdered to 3 sizes. The nanomangosteen peel ethanol extract was encapsulated in various of concrentration chitosan. The particle size of encapsulated products were determined by particle size analyzer (PSA) and also analyzed of antibacterial activities. The nanomangosteen peel extract showed antibacterial activity stronger impact to 3 tested bacterial: S. aureus, B. cereus, and S. flexinery than 40 mesh and 20 mesh size. Encapsulated of nanomagosteen peel extract with chitosan showed that the particle size of PN, AN, and BN were 308.30, 342.42, and 421.26 nm respectively with polydispersity index (PI) of 0.14, 0.31, and 0.11 respectively, however antimicrobial activities of encapsulated products still have not satisfied yet. (paper)