Published November 2018 | Version v1
Journal article Metadata-only

Detection and analysis of MXR7 gene expression in human liver cells induced by radiation and peripheral blood of radiation workers

Creators

  • 1. China Institute of Atomic Energy, Beijing (China)
  • 2. China Institute for Radiation Protection, Taiyuan (China)
  • 3. Heping Hospital Affiliated to Changzhi Medical College, Changzhi (China)

Description

In order to explore the changes of MXR7 genes expression in human liver cells HL-7702 and peripheral blood induced by radiation, the expression changes of MXR7 gene in human liver cells irradiated by 60Co γ-ray were detected by real-time fluorescent quantitative PCR. Furthermore, MXR7 gene expression levels were detected in peripheral blood from radiation workers. Results showed that ionizing radiation can induce the change of MXR7 genes expression in human liver cells, and it is dose-related. The expression of MXR7 gene in peripheral blood from radiation workers was up-regulated to compare with the expression of non-radiation workers. (authors)

Additional details

Publishing Information

Journal Title
Radiation Protection (Taiyuan)
Journal Volume
38
Journal Issue
6
Journal Page Range
p. 517-521
ISSN
1000-8187

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
54035602
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BLOOD; COBALT 60; COMPARATIVE EVALUATIONS; FLUORESCENCE; GAMMA RADIATION; GENES; LIVER CELLS; MEN; POLYMERASE CHAIN REACTION; RADIATION DOSES; RADIOLOGICAL PERSONNEL
Descriptors DEC
ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BODY FLUIDS; COBALT ISOTOPES; DOSES; ELECTROMAGNETIC RADIATION; EMISSION; EVALUATION; GENE AMPLIFICATION; HUMANS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LUMINESCENCE; MALES; MAMMALS; MATERIALS; MEDICAL PERSONNEL; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; PERSONNEL; PHOTON EMISSION; PRIMATES; RADIATIONS; RADIOISOTOPES; SOMATIC CELLS; VERTEBRATES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
4 figs., 3 tabs., 11 refs.