Published 2000
| Version v1
Miscellaneous
Non-linear model for the kinetics of 10B in blood after BPA-fructose complex infusion in BNCT
Creators
- 1. University of Helsinki (Finland). Department of Physics
- 2. VTT Technology, Espoo (Finland)
Description
The purpose of the study was to create non-linear model for estimating the blood 10B time-concentration after p-boronophenylalanine fructose complex (BPA-F) infusion in patients undergoing boron neutron capture therapy (BNCT). The models were applied to data from 8 patients who were part of the phase I BNCT clinical trial at Brookhaven National Laboratory (BNL). All patients received a two-hour infusion of BPA-F of 290 mg BPA/kg body weight, with the infusion speed adjusted to the body weight of each patient. Blood samples were collected during and after the infusion. The model development is based on averaged and interpolated data from data sets of these patients
Additional details
Publishing Information
- ISBN
- 951-22-4897-2
- Imprint Title
- Proceedings of the XXXIV annual conference of the Finnish Physical Society
- Imprint Pagination
- 366 p.
- Journal Page Range
- p. 164
- Report number
- TKK-F-A--797
Conference
- Title
- 34. annual conference of the Finnish Physical Society
- Dates
- 9-11 Mar 2000
- Place
- Espoo (Finland)
INIS
- Country of Publication
- Finland
- Country of Input or Organization
- Finland
- INIS RN
- 32030744
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Non-conventional Literature, Conference
- Descriptors DEI
- BLOOD CIRCULATION; BORON 10; CONCENTRATION RATIO; INFUSION; NEUTRON CAPTURE THERAPY; ORGANIC BORON COMPOUNDS; TIME DEPENDENCE
- Descriptors DEC
- BORON ISOTOPES; INTAKE; ISOTOPES; LIGHT NUCLEI; MEDICINE; NEUTRON THERAPY; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; RADIOLOGY; RADIOTHERAPY; STABLE ISOTOPES; THERAPY
Optional Information
- Notes
- Published only in abstract form