Published December 1976 | Version v1
Journal article Metadata-only

Hemopoietic stem cell kinetics in 4000 r irradiated spleens

Creators

  • 1. Univ. of Southern California, Los Angeles

Description

The kinetics of hemopoietic stem cells have been studied after the whole or a portion of the mouse spleen was exposed to 4000 rads. The results point out that stem cell renewal in vivo is dependent on microdiffusion of a stimulus produced by highly radioresistant, specialized cells. The existence of these cells, called ''sources,'' can at present be inferred only according to functional and radiobiologic criteria

Additional details

Additional titles

Augmented title (English)
Electrons

Publishing Information

Journal Title
RES, J. Reticuloendothel. Soc.
Journal Volume
20
Journal Issue
6
Series
RES, J. Reticuloendothel. Soc.
Journal Page Range
429-446

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
9382622
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; BLOOD FORMATION; ELECTRONS; KINETICS; LINEAR ACCELERATORS; MICE; SPLEEN; STEM CELLS
Descriptors DEC
ACCELERATORS; ANIMAL CELLS; ANIMALS; BIOLOGICAL EFFECTS; BODY; ELEMENTARY PARTICLES; FERMIONS; LEPTONS; MAMMALS; ORGANS; RADIATION EFFECTS; RODENTS; SOMATIC CELLS; VERTEBRATES