Combination of cardiac function determination by list mode first pass and myocardial perfusion imaging with ATP loading in diagnosis of coronary artery disease

Objective: To study the diagnostic value of cardiac function determination by list mode first pass in combination with myocardial perfusion imaging at ATP stress in coronary artery disease. Methods: The patients were divided into the group with coronary artery disease (n = 97) and the control group (n = 36). Cardiac function was determined by list mode first pass with ATP stress, then myocardial perfusion imaging was performed 90 min after injection of 99Tcm-MIBI, 52 of the stress results were compared with that of rest examination. Results: The sensitivity and specificity of myocardial perfusion imaging at ATP stress in diagnosis of coronary artery disease were higher than those of rest examination (P < 0.05), so were the accuracy of those (P < 0.01) and the sensitivity and accuracy of cardiac function determination (P < 0.05). Cardiac function deterioration and heart dilatation in various levels, even heart-lung blood flow dynamic change were detected in myocardial infarction group, in which 52.38% of infarction segments exerted ventricular wall motion. Conclusions: This combination of the two modalities could simultaneously evaluate myocardial perfusion, myocardial diastolic-systolic function, heart-lung blood flow dynamics, ventricular remodeling, cardiac aneurysm and myocardial viability, then upgrade the diagnosis value in coronary artery disease