Published August 1976
| Version v1
Journal article
Distribution study of 57Co-, 51Cr-, 111In- and sup(99m)Tc- bleomycin in solid Ehrlich-carcinoma bearing mice
Description
From the comparative studies of 57Co-, 51Cr-, 111In- and sup(99m)Tc-Bleomycin using 282 solid Ehrlich-carcinoma-bearing mice, 57Co was found to be the most suitable bleomycin preparation for tumor scintigraphy. The results obtained by 111In-Bleomycin of linear tumor cell absorption indicates a possible use of 111In-Bleomycin as an agent for objective histological differentiation also in cells previously treated with therapeutic agents. (orig.)
Abstract (German)
Anhand der Verteilungsstudie von 57Co-, 51Cr-, 111In-und 99mTc-Bleomycin an 282 Mäusen mit einem soliden Ehrlich-Karzinom ist 57Co-Bleomycin am besten zur allgemeinen Tumorszintigraphie geeignet. Die Beobachtung über einen nahezu linearen 111In-Einbau in das Tumorgewebe (8—48 Std. post in-jektionem) stellt möglicherweise ein Hilfsmittel zur Objektivierung histologischer Differenzen und therapeutischer Maßnahmen im malignen Gewebe dar.Additional details
Additional titles
- Original title (German)
- Verteilungsstudie mit
Identifiers
Publishing Information
- Journal Title
- Nuklearmedizin
- Journal Volume
- 15
- Journal Issue
- 04
- Series
- Nucl.-Med.
- Journal Page Range
- 176-182
- ISSN
- 0029-5566
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 7278753
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- ASCITES TUMOR CELLS; BLEOMYCIN; CHROMIUM 51; DISTRIBUTION; DNA; EHRLICH ASCITES TUMOR; HALF-LIFE; INDIUM 111; ISOMERIC NUCLEI; MICE; RADIONUCLIDE KINETICS; TECHNETIUM 99
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; ANTIBIOTICS; ANTIMITOTIC DRUGS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CHROMIUM ISOTOPES; DAYS LIVING RADIOISOTOPES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-ODD NUCLEI; EXPERIMENTAL NEOPLASMS; HOURS LIVING RADIOISOTOPES; INDIUM ISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; KINETICS; MAMMALS; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEI; NUCLEIC ACIDS; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; RADIOISOTOPES; RODENTS; TECHNETIUM ISOTOPES; TUMOR CELLS; VERTEBRATES; YEARS LIVING RADIOISOTOPES
Optional Information
- Notes
- 7 figs.; 5 tabs.; 12 refs.; Updated automatically by Metadata and Full-Text Enrichment Agent