Published March 1, 1986 | Version v1
Journal article Metadata-only

Effect of sex on the characteristics of autonomic receptors in lower urinary tract

Creators

  • 1. Yale Univ. School of Medicine, New Haven, CT

Description

Since there are conflicting reports regarding the composition of autonomic receptors in the lower urinary tract, characteristics of adrenergic and muscarinic cholinergic receptors were investigated in six month old male and female rabbits. The authors utilized the 3H-prazosin (PZ), 3H-yohimbine (YOH), 3H-dihydroalprenolol (DHA) and 3H-quinuclidinyl benzylate (QNB) to label alpha-1, alpha-2, and beta adrenergic and muscarinic receptors, respectively, in plasma membranes of bladder base, bladder dome and urethra. Saturation experiments were performed to determine K/sub D and B/sub max/ values. K/sub D/ values for each labeled ligand were similar in all examined tissues and sexes

Additional details

Publishing Information

Journal Title
Fed. Proc., Fed. Am. Soc. Exp. Biol.
Journal Volume
45
Journal Issue
3
Series
Fed. Proc., Fed. Am. Soc. Exp. Biol.
Journal Page Range
565
CODEN
FEPRA

Conference

Title
70. annual meeting of the Federation of American Society for Experimental Biology.
Dates
13-18 Apr 1986.
Place
St. Louis, MO (USA).

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
17088083
Subject category
S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CELL MEMBRANES; LIGANDS; RABBITS; RECEPTORS; SEX DEPENDENCE; SYMPATHOMIMETICS; TRACER TECHNIQUES; TRITIUM COMPOUNDS; URINARY TRACT
Descriptors DEC
ANIMALS; AUTONOMIC NERVOUS SYSTEM AGENT; BODY; CELL CONSTITUENTS; DRUGS; HYDROGEN COMPOUNDS; ISOTOPE APPLICATIONS; MAMMALS; MEMBRANES; ORGANS; VERTEBRATES

Optional Information

Secondary number(s)
CONF-8604222--.