Facile synthesis of multisegment Au/Ni/Au nanowire for high performance electrochemical glucose sensor

This paper reported an electrochemical potentiometric glucose biosensor, developed by immobilizing glucose oxidase on an electrode consisting of Au/Ni/Au nanowires. Electrochemically deposited nanowires are bridged between two gold electrodes. Field emission scanning electron microscope (FESEM) and energy-dispersive x-ray spectroscopy (EDS) are used for the morphological characterization of nanostructures. The device is tested by electrochemical potentiometric and simple IV measurement techniques. In order to check the glucose potentiometric response, nanowires are coated with enzyme, glucose oxidase which revealed a glucose dependant electrochemical response versus reference electrode (Ag/AgCl). Electrochemical response of the sensor is found to be linear in range of 0.5–10 mM. Fabrication of Au/Ni/Au nanowires by facile method will provide the opportunity for glucose biosensors to measure glucose by simple and direct technique. (paper)