Published 1986 | Version v1
Book Metadata-only

Genetic and biochemical characteristics of three different types of mutants of mammalian cells affected in adenosine kinase

Creators

  • 1. McMaster University, Hamilton

Description

Previous studies of cellular mutants resistant to various analogs initially selected are studied and their cross resistance patterns towards other nucleoside analogs and the affected cellular functions are examined. The cellular uptake of tritium-adenosine, tritium-tubercidin, and tritium-formycin by various cell lines is shown. Adenosine kinase activity in the mutant cell extracts are discussed. A table present the genetic and biochemical characteristics of different types of mutants affected in AK

Additional details

Publishing Information

Publisher
Plenum Press.
Imprint Place
New York, NY (USA)
Imprint Title
Purine and pyrimidine metabolism in man V
Journal Page Range
p. 595-603.

Conference

Title
5. international symposium on human purine and pyrimidine metabolism.
Dates
28 Jul - 1 Aug 1985.
Place
San Diego, CA (USA).

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
18051156
Subject category
S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ADENOSINE; ANTIMETABOLITES; BIOCHEMICAL REACTION KINETICS; BIOCHEMISTRY; BIOLOGICAL EFFECTS; BIOSYNTHESIS; CELL CULTURES; CHO CELLS; ENZYME ACTIVITY; GENETICS; METABOLISM; MUTANTS; PHOSPHORYLATION; PHOSPHOTRANSFERASES; PURINES; RADIOENZYMATIC ASSAY; TRITIUM COMPOUNDS; UPTAKE
Descriptors DEC
ANIMAL CELLS; BIOLOGY; CHEMICAL REACTIONS; CHEMISTRY; DRUGS; ENZYMES; HETEROCYCLIC COMPOUNDS; HYDROGEN COMPOUNDS; KINETICS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PHOSPHORUS-GROUP TRANSFERASES; REACTION KINETICS; RIBOSIDES; SOMATIC CELLS; SYNTHESIS; TRANSFERASES