Post prostatectomy radiotherapy: our experience

Full text: Background: Between 2000 and 2005, at Vidt Medical Center, 85 patients were treated with 3D and IMRT radiotherapy after undergoing radical prostatectomy for localized prostate adenocarcinoma. Objective: To evaluate biochemical recurrence and specific disease free survival and global survival. Materials and method: These patients were divided into two groups: those who engaged in what is called adjuvant therapy (20 patients), who after surgery had increased risk factors and / or persistence of the disease. These risk factors were positive margins, seminal vesicles involvement, capsule infiltration or persistent PSA. The other group were 65 patients referred to as rescue therapy: they were those that presented PSA increase after having undetectable levels as observed nadir after surgery, understanding > 0.2 ng / ml as a high value or palpable nodule on rectal touch with or without positive biopsy. Follow up was between 24 and 84 months, the dose delivered was between 6500 - 7000 cGy. Also evaluated the early and late toxicity, urinary and rectal, according to RTOG criteria. Conclusion: The results obtained confirm the benefits of postoperative radiation therapy for both groups of patients, showing a more favorable trend on those treated with adjuvant therapy. (authors)