On the possibility of study the surface structure of small bio-objects, including fragments of nucleotide chains, by means of electron interference
Creators
- 1. Institute of Nuclear Physics, Moscow State University, Vorobyovy Gory, 119992 Moscow (Russian Federation)
Description
We propose a new method to study the surface of small bio-objects, including macromolecules and their complexes. This method is based on interference of low-energy electrons. Theoretically, this type of interference may allow to construct a hologram of the biological object, but, unlike an optical hologram, with the spatial resolution of the order of inter-atomic distances. The method provides a possibility to construct a series of such holograms at various levels of electron energies. In theory, obtaining such information would be enough to identify the types of molecular groups existing on the surface of the studied object. This method could also be used for 'fast reading' of nucleotide chains. It has been shown how to depose a long linear molecule as a straight line on a substrate before carrying out such 'reading'.
Availability note (English)
Available from http://dx.doi.org/10.1016/j.physleta.2008.12.075Additional details
Identifiers
- DOI
- 10.1016/j.physleta.2008.12.075;
- PII
- S0375-9601(09)00672-0;
Publishing Information
- Journal Title
- Physics Letters. A
- Journal Volume
- 373
- Journal Issue
- 31
- Journal Page Range
- p. 2608-2613
- ISSN
- 0375-9601
- CODEN
- PYLAAG
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 41077511
- Subject category
- S74: ATOMIC AND MOLECULAR PHYSICS;
- Descriptors DEI
- ELECTRONS; HOLOGRAPHY; INTERFERENCE; MOLECULES; NUCLEOTIDES; SPATIAL RESOLUTION; SUBSTRATES; SUBSURFACE STRUCTURES
- Descriptors DEC
- ELEMENTARY PARTICLES; FERMIONS; LEPTONS; ORGANIC COMPOUNDS; RESOLUTION
Optional Information
- Copyright
- Copyright (c) 2009 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.