Published July 20, 2009 | Version v1
Journal article

On the possibility of study the surface structure of small bio-objects, including fragments of nucleotide chains, by means of electron interference

Creators

  • 1. Institute of Nuclear Physics, Moscow State University, Vorobyovy Gory, 119992 Moscow (Russian Federation)

Description

We propose a new method to study the surface of small bio-objects, including macromolecules and their complexes. This method is based on interference of low-energy electrons. Theoretically, this type of interference may allow to construct a hologram of the biological object, but, unlike an optical hologram, with the spatial resolution of the order of inter-atomic distances. The method provides a possibility to construct a series of such holograms at various levels of electron energies. In theory, obtaining such information would be enough to identify the types of molecular groups existing on the surface of the studied object. This method could also be used for 'fast reading' of nucleotide chains. It has been shown how to depose a long linear molecule as a straight line on a substrate before carrying out such 'reading'.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.physleta.2008.12.075

Additional details

Identifiers

DOI
10.1016/j.physleta.2008.12.075;
PII
S0375-9601(09)00672-0;

Publishing Information

Journal Title
Physics Letters. A
Journal Volume
373
Journal Issue
31
Journal Page Range
p. 2608-2613
ISSN
0375-9601
CODEN
PYLAAG

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
41077511
Subject category
S74: ATOMIC AND MOLECULAR PHYSICS;
Descriptors DEI
ELECTRONS; HOLOGRAPHY; INTERFERENCE; MOLECULES; NUCLEOTIDES; SPATIAL RESOLUTION; SUBSTRATES; SUBSURFACE STRUCTURES
Descriptors DEC
ELEMENTARY PARTICLES; FERMIONS; LEPTONS; ORGANIC COMPOUNDS; RESOLUTION

Optional Information

Copyright
Copyright (c) 2009 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.