Diagnostic accuracy of fine needle biopsy in the management of thyroid pathology in the Hospital Mexico in 2011-2012
Description
The nodule has been a very common thyroid pathology; through palpation is located in a 5% of the population and through ultrasound this figure has increased by almost 50%. The thyroid nodule has been the shape of presentation of thyroid cancer; the majority of times asymptomatic and most recently has shown without relation to the size of the nodule, 5 to 15% of thyroid nodules are malignant. This requires to classify clinically, to decide which patient requires surgical management. In Costa Rica, and especially in the CCSS (Caja Costarricense de Seguro Social); It has had two tools for perform differentiation: ultrasound and FNA (fine needle aspiration biopsy). The diagnostic accuracy of these tests has allowed minimize thyroid surgeries in patients with benign nodules and sift patients with thyroid nodules into search for cancer of thyroid. Previous to routine use of FNA was resected only 14% of malignant nodules, now are resected more than 50%. The diagnostic accuracy of these tests is related to technical aspects and also with the structural and histological features of the lesions valued. The limitations and scope described have allowed to optimize the utilization of direct and indirect costs related to the management of patients with thyroid nodules and decrease morbidity in the management of thyroid pathology. The sensitivity and specificity of fine needle biopsy varies, as is noted in various publications, according to the reference center, has been quite reliable between 0.3 and 3 cm and is highly specific in the case of papillary carcinoma. The diagnostic accuracy of the test has never been studied in the Hospital Mexico. Of the total population for the period 2011-2012, it is documented that the FNA is a study of high specificity (95,5%), with value predictive negative and positive appropriate (>75%) and with an intermediate sensitivity (55,6%). The analysis of ultrasound and FNA as parallel testing has allowed greater sensitivity. The use of ultrasound to guide the biopsy has increased the sensitivity of the study to 70%; a finding that could have an impact on the daily clinical work. (author)
Availability note (English)
Available from Biblioteca Luis Demetrio Tinoco, Universidad de Costa RicaAbstract (Spanish)
El nodulo ha sido una patologia tiroidea muy comun; mediante palpacion es encontrado en el 5% de la poblacion y mediante ultrasonido esta cifra ha aumentado en casi un 50%. El nodulo tiroideo ha sido la forma de presentacion del cancer de tiroides; la mayoria de las veces asintomatico y mas recientemente se ha demostrado que existe sin relacion al tamano del nodulo, 5 al 15% de los nodulos tiroideos son malignos. Ello obliga a clasificarlos clinicamente, para decidir cual paciente requiere manejo quirurgico. En Costa Rica, y especialmente en la CCSS (Caja Costarricense de Seguro Social); se ha contado con dos herramientas para realizar la diferenciacion: el ultrasonido y la BAAF (biopsia de aspiracion por aguja fina). La precision diagnostica de estas pruebas ha permitido minimizar las cirugias tiroideas en pacientes con nodulos benignos y tamizar los pacientes con nodulos tiroideos en busqueda de cancer de tiroides. Previo al uso rutinario de la BAAF se resecaban solo el 14% de los nodulos malignos, ahora son resecados mas del 50%. La precision diagnostica de estas pruebas es relacionada con aspectos tecnicos y asi mismo con las caracteristicas estructurales e histologicas de las lesiones valoradas. Las limitaciones y alcances descritos han permitido optimizar la utilizacion de costos directos e indirectos relacionados con el manejo de los pacientes con nodulos tiroideos y disminuir de la morbilidad en el manejo de la patologia tiroidea. La sensibilidad y especificidad de la biopsia por aguja fina varia, segun es anotado en diferentes publicaciones, de acuerdo con el centro de referencia, ha sido bastante fiable entre 0.3 y 3 cm y es altamente especificada en el caso del carcinoma papilar. La precision diagnostica de la prueba nunca ha sido estudiada en el Hospital Mexico. De la poblacion total del periodo 2011-2012, es documentado que la BAAF ha sido un estudio de alta especificidad (95,5%), con valor predictivo negativo y positivo adecuados (>75%) y con una sensibilidad intermedia (55,6%). El analisis del ultrasonido y la BAAF como pruebas en paralelo han permitido mayor sensibilidad. El uso del ultrasonido para dirigir la biopsia ha incrementado la sensibilidad del estudio a un 70%; un hallazgo que podria tener impacto en el trabajo clinico diario. (autor)Additional details
Additional titles
- Original title (Spanish)
- Precision diagnostica de la biopsia por aguja fina en el manejo de patologia tiroidea en el Hospital Mexico en el periodo 2011-2012
Publishing Information
- Imprint Place
- San Jose (Costa Rica)
- Imprint Pagination
- 64 p.
INIS
- Country of Publication
- Costa Rica
- Country of Input or Organization
- Costa Rica
- INIS RN
- 46081998
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Numerical Data, Thesis, Non-conventional Literature
- Descriptors DEI
- BIOPSY; DIAGNOSIS; ENDOCRINE GLANDS; HOSPITALS; IMAGE PROCESSING; IMAGES; NEOPLASMS; NUMERICAL DATA; PATHOLOGY; PATIENTS; THYROID; THYROID CELLS; THYROID HORMONES; TSH; ULTRASONOGRAPHY
- Descriptors DEC
- ANIMAL CELLS; BODY; BUILDINGS; DATA; DIAGNOSTIC TECHNIQUES; DISEASES; ENDOCRINE GLANDS; GLANDS; HORMONES; INFORMATION; MEDICAL ESTABLISHMENTS; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HORMONES; PITUITARY HORMONES; PROCESSING; PROTEINS; SOMATIC CELLS
Optional Information
- Notes
- Tabs., ills., refs.