Published March 1995 | Version v1
Journal article

On the role of endogenous opioid system in the mechanisms of the development of early post-irradiation vegetative and behavioural disturbances

  • 1. Ministerstvo-Oborony, Sankt-Peterburg (Russian Federation). Nauchno-Issledovatel'skij Inst. Voennoj Meditsiny

Description

In the experiments with rats and dogs it was shown that irradiation within the dose range of 50-100 Gy is accompanied by the increasing of enkephaline content in various brain structures and β-endorphine level in blood plasma. The blocking of the opial receptors naloxone promotes the decrease of post-radiation vomiting in dogs, gastrostasis and hypokinesia in rats. That supports the participation of endogenous opioid system in the primary clinical reaction response to irradiation. 15 refs.; 3 figs

Additional details

Additional titles

Original title (Russian)
К вопросу о роли эндогенной опиоидной системы в механизмах развития ранних постлучевых вегетативных и новеденческих нарушений

Publishing Information

Journal Title
Radiatsionnaya Biologiya, Radioehkologiya
Journal Volume
35
Journal Issue
2
Journal Page Range
p. 195-199.
ISSN
0869-8031
CODEN
RBIREJ