Published December 1, 1994 | Version v1
Journal article Metadata-only

An improved procedure for the synthesis of 2-methoxyisobutylisonitrile. An efficient complexing agent for 99mTc

Creators

  • 1. Instituto Nacional de Investigaciones Nucleares, Mexico City (Mexico)
  • 2. Universidad Autonoma del Estado de Morelos (UAEM), Cuernavaca (Mexico)

Description

99mTc hexakis(2-methoxyisobutylisonitrile) is a cationic complex useful as a myocardial perfusion agent. The synthesis of 2-methoxyisobutylisonitrile (MIBI) by a modified and improved procedure in a twostep process with an overall yield of 53% is described. The preparation of its copper and technetium-99m complexes is also presented. (author) 5 refs

Additional details

Publishing Information

Journal Title
Journal of Radioanalytical and Nuclear Chemistry
Journal Volume
188
Journal Issue
6
Journal Page Range
p. 409-415.
ISSN
0236-5731
CODEN
JRNCDM

INIS

Country of Publication
Hungary
Country of Input or Organization
Hungary
INIS RN
26028215
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CHEMICAL PREPARATION; CHEMICAL REACTION YIELD; COPPER COMPLEXES; ISONITRILES; RADIOPHARMACEUTICALS; TECHNETIUM COMPLEXES; TECHNETIUM 94
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBONIC ACID DERIVATIVES; COMPLEXES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SYNTHESIS; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPLEXES; YIELDS