Strontium - 89 combined with technetium - 99 methylenediphosphonate for the treatment of malignant bony metastasis in the patients with advanced prostate cancer
- 1. Department of Urology, the Second Hospital Affiliated to Suzhou University, Suzhou (China)
Description
Objective: This work was done to evaluate the effectiveness and side effects of the therapy of radioactive nuclide strontium - 89 (89Sr) and technetium - 99 methylenediphosphonate (99Tc - MDP) for malignant bony metastasis in the patients with advanced prostate cancer. Methods: Twenty patients with skeletal metastasis received this treatment of 89Sr and 99Tc - MDP. The patients were observed and followed up with respect to pain control, lesion improvement and side effects. Results: The overall effective rate of pain control was 86.66%. The lesion in eight patients as assessed by SPECT imaging, was improved. The main side effect was the mild recoverable descent of leukocytes and thrombocytes. Conclusion: The treatment of 89Sr and 99Tc - MDP is very useful for malignant bony metastasis in patients with advanced prostate cancer, especially for metastatic bone pain
Additional details
Publishing Information
- Journal Title
- Acta Academiae Medicinae Suzhou
- Journal Volume
- 23
- Journal Issue
- 5
- Journal Page Range
- p. 553-554, 603
- ISSN
- 1000-5749
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 35092897
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- COMBINED THERAPY; METASTASES; METHYLENE RADICALS; NEOPLASMS; PAIN; PHOSPHONATES; PROSTATE; RADIOTHERAPY; SIDE EFFECTS; SKELETAL DISEASES; STRONTIUM 89; TECHNETIUM 99
- Descriptors DEC
- ALKALINE EARTH ISOTOPES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; DAYS LIVING RADIOISOTOPES; DISEASES; EVEN-ODD NUCLEI; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MALE GENITALS; MEDICINE; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC PHOSPHORUS COMPOUNDS; ORGANS; RADICALS; RADIOISOTOPES; RADIOLOGY; STRONTIUM ISOTOPES; SYMPTOMS; TECHNETIUM ISOTOPES; THERAPY; YEARS LIVING RADIOISOTOPES