Published 2000
| Version v1
Report
Open
Development of Re-188 radiolabelling procedures of peptides and monoclonal antibodies
Creators
- 1. E-mail: vlungu at ifin.nipne.ro (Romania)
- 2. Institute of Physics and Nuclear Engineering, Horia Hulubei, Radiopharmaceuticals Labelled compounds and Industrial Radioactive Source Department, Bucharest (Romania).
Description
The goal of this work was to study and select the parameters to label biomolecules directly with 188Re. The concrete objectives pursued were: (i) Labelling h-IgG with 188Re; (ii) Radiolabelling Lanreotide and anti-CEA monoclonal antibody with 188Re; investigation of chromatography based quality control techniques; (iii) Biodistribution studies in tumour bearing rats
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Additional details
Publishing Information
- Imprint Title
- Report of the research co-ordination meeting on labelling techniques of biomolecules for targeted radiotherapy
- Imprint Pagination
- 92 p.
- Journal Page Range
- p. 71-78
- Report number
- INIS-XA--262
Conference
- Title
- 2. research co-ordination meeting of the co-ordinated research programme on labelling techniques of biomolecules for targeted radiotherapy
- Dates
- 31 Jan - 4 Feb 2000
- Place
- Mumbai (India)
INIS
- Country of Publication
- International Atomic Energy Agency (IAEA)
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 31027876
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- CHEMICAL PREPARATION; LABELLING; LYOPHILIZATION; MONOCLONAL ANTIBODIES; PEPTIDES; QUALITY CONTROL; RHENIUM 188
- Descriptors DEC
- ANTIBODIES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CONTROL; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; PROTEINS; RADIOISOTOPES; RHENIUM ISOTOPES; SYNTHESIS
Optional Information
- Notes
- 5 figs, 4 tabs