Published August 1993
| Version v1
Journal article
Introduction of five potentially metabolizable linking groups between 111In-cyclohexyl EDTA derivatives and F(ab')2 fragments of anti-carcinoembryonic antigen antibody: Pt. 2
Creators
- 1. INSERM, 44 - Nantes (France)
- 2. Brookhaven National Lab., Upton, NY (United States)
Description
The five chelating linker-containing immunoconjugates previously described by the authors were labeled with 111In and tested for their biodistribution, pharmacokinetics and immunoscintigraphic imaging properties in tumor-xenografted nude mice. The results were compared with DTPADA and CDTAMA for reference. (author)
Additional details
Additional titles
- Subtitle (English)
- Comparative pharmacokinetics and biodistribution in human colorectal carcinoma-bearing nude mice
Publishing Information
- Journal Title
- Nuclear Medicine and Biology
- Journal Volume
- 20
- Journal Issue
- 6
- Journal Page Range
- p. 763-771.
- ISSN
- 0883-2897
- CODEN
- NMBIEO
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 25025534
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CARCINOMAS; CDTA; CHELATING AGENTS; COMPARATIVE EVALUATIONS; EDTA; IMAGES; INDIUM 111; LABELLED COMPOUNDS; MAN; MICE; MONOCLONAL ANTIBODIES; RADIONUCLIDE KINETICS; RECTUM; SCINTISCANNING; SPATIAL RESOLUTION
- Descriptors DEC
- AMINO ACIDS; ANIMALS; ANTIBODIES; BETA DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; EVALUATION; GASTROINTESTINAL TRACT; INDIUM ISOTOPES; INTERMEDIATE MASS NUCLEI; INTESTINES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; KINETICS; LARGE INTESTINE; MAMMALS; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; PRIMATES; RADIOISOTOPE SCANNING; RADIOISOTOPES; RESOLUTION; RODENTS; VERTEBRATES