Organ-specific TDF distribution
- 1. Nagoya Univ. (Japan). Coll. of Medical Technology (Japan)
Description
The concept of Nominal Standard Dose (NSD) determined from the time dose fractionation relation between acute reaction of skin and normal connective tissue to radiation, was suggested by F. Ellis. Using Ellis' formula, C. G. Orton proposed the time, dose, and fractionation (TDF) factor. The TDF value is generally used to evaluate tolerance of normal connective tissue. However, the TDF is not applicable to other organs such as the spinal cord and lungs. Cohen, using data from radiation complications, has determined exponents of the Ellis' formula for some organs. From those formulae, we have calculated organ-specific TDFs, based on treatment schedule and dose distribution. In the case of esophageal cancer, organ-specific TDF distributions of the irradiation technique were compared and evaluated. (author)
Additional details
Publishing Information
- Journal Title
- Nippon Hoshasen Shuyo Gakkai-Shi
- Journal Volume
- 5
- Journal Issue
- 4
- Journal Page Range
- p. 253-260.
- ISSN
- 1040-9564
- CODEN
- JOJAEA
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 25044187
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BRAIN; CARCINOMAS; CONNECTIVE TISSUE; ESOPHAGUS; EXTERNAL IRRADIATION; FRACTIONATED IRRADIATION; IRRADIATION PROCEDURES; LUNGS; PATIENTS; RADIATION DOSES; RADIATION INJURIES; RADIOTHERAPY; SPATIAL DOSE DISTRIBUTIONS; SPINAL CORD
- Descriptors DEC
- ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CENTRAL NERVOUS SYSTEM; DIGESTIVE SYSTEM; DISEASES; DISTRIBUTION; INJURIES; IRRADIATION; MAMMALS; MAN; MEDICINE; NEOPLASMS; NERVOUS SYSTEM; ORGANS; PRIMATES; RADIATION DOSE DISTRIBUTIONS; RADIATION EFFECTS; RESPIRATORY SYSTEM; SPATIAL DISTRIBUTION; THERAPY; TISSUES; VERTEBRATES