Published September 2015 | Version v1
Journal article Metadata-only

Accuracy of TOMPOOL (gated blood pool SPECT processing software) for the assessment of bi-ventricular volumes and ejection fraction

Creators

  • 1. Gustave Roussy, Cancer Campus, 94805 Villejuif (France)
  • 2. Departement de medecine nucleaire, CHU de Toulouse, 31059 Toulouse cedex 09 (France)
  • 3. Departement de radiologie, CHU de Toulouse, 31059 Toulouse (France)
  • 4. Departement de biostatistiques, institut Claudius-Regaud, 20-24, rue du Pont-Saint-Pierre, 31052 Toulouse (France)
  • 5. Faculte de medecine de Rangueil, universite Paul-Sabatier, Toulouse (France)
  • 6. Centre d'imagerie cardiaque, CHU de Toulouse, 31059 Toulouse (France)
  • 7. Departement de cardiologie, CHU de Toulouse, 31059 Toulouse (France)

Description

Background. - To evaluate the diagnostic accuracy of TOMPOOL (gated blood pool SPECT). Comparison with a reference-algorithm: BPSPECT. Comparison with MRI and right heart catheter measurement. Estimation of the inter-observer reproducibility. Methods and results. - Ninety-nine consecutive patients underwent GBPS and two physicians performed the measurement using TOMPOOL and BP-SPECT. Results were compared to the recommended reference-standard: cardiac magnetic resonance imaging [CMR] (EDV, ESV, EF, n = 35), catheter measurements from thermodilution [TD] (CO, n = 21). Results. - Results are always referred using the following order: correlation with BP-SPECT (n = 99), correlation with reference-standard (MRI or right heart catheter measurement), inter-observer correlation. RVEF: r = 0.67; r = 0.70; r = 0.81. RVEDV: r = 0.74; r = 0.49; r = 0.77. RVESV: r = 0.76; r = 0.64; r = 0.81. RCO: r = 0.68; 0.63; 0.78. LVEF: r = 0.88; r = 0.79; r = 0.94. LVEDV: r = 0.82; r = 0.80; r = 0.90. LVESV: r = 0.89; r = 0.90; 0.95. Conclusion. - TOMPOOL allows a quantitative and qualitative analysis of the volume and systolic function of the left ventricle. However, a prior CMR-based calibration is preferable (thresholds must be adjusted). A qualitative analysis of the right ventricle is more reliable (poorer correlation and reproducibility). (authors)

Availability note (English)

Available from doi: http://dx.doi.org/10.1016/j.mednuc.2015.04.002

Abstract (French)

But de l'etude. - Evaluation des performances du logiciel de ventriculographie isotopique a l'equilibre 3D (V3D) TOMPOOL. Comparaison avec un logiciel de reference : BP-SPECT. Comparaison avec l'IRM et le catheterisme droit. Evaluation de la reproductibilite des mesures. Materiel (ou patients) et methodes. - Quatre-vingt-dix-neuf V3D furent traitees par deux observateurs en utilisant les logiciels TOMPOOL et BPSPECT. Les resultats furent compares a 35 IRM (VTD, VTS, FE) et 21 catheterismes droits (QD). Resultats. - Les resultats sont donnes dans l'ordre suivant : correlation avec BP-SPECT (n = 99) ; correlation avec le standard de reference (IRM, n = 35 ; catheterisme droit, n = 21, reference uniquement pour l'estimation du debit droit) ; correlation inter-observateur. FEVD : r = 0,67 ; r = 0,70 ; r = 0,81. VTDVD : r = 0,74 ; r = 0,49 ; r = 0,77. VTSVD : r = 0,76 ; r = 0,64 ; r = 0,81. Debit droit : r = 0,68 ; 0,63 ; 0,78. FEVG : r = 0,88 ; r = 0,79 ; r = 0,94. VTDVG : r = 0,82 ; r = 0,80 ; r = 0,90. VTSVG : r = 0,89 ; r = 0,90 ; r = 0,95. Conclusion. - Les resultats dependent du logiciel de V3D utilise. Une calibration par IRM est necessaire pour permettre une analyse quantitative (valeurs moyennes differentes) ou une analyse qualitative (seuils differents) de la fonction ou des volumes bi-ventriculaires. En routine, une analyse quantitative a gauche et qualitative a droite est sans doute a privilegier. (auteurs)

Additional details

Additional titles

Original title (French)
Performance et reproductibilite de TOMPOOL pour l'estimation des fractions d'ejection, volumes et debits bi-ventriculaires

Identifiers

DOI
10.1016/j.mednuc.2015.04.002;

Publishing Information

Journal Title
Medecine Nucleaire. Imagerie Fonctionnelle et Metabolique
Journal Volume
39
Journal Issue
no.4
Journal Page Range
p. 371-379
ISSN
0928-1258
CODEN
MNIMEX

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
53085791
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ACCURACY; ALGORITHMS; BLOOD; CARBON MONOXIDE; CHEST; COMPUTER CODES; DIAGNOSIS; HEART; NMR IMAGING; PATIENTS; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
Descriptors DEC
BIOLOGICAL MATERIALS; BODY; BODY FLUIDS; CARBON COMPOUNDS; CARBON OXIDES; CARDIOVASCULAR SYSTEM; CHALCOGENIDES; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; EMISSION COMPUTED TOMOGRAPHY; MATERIALS; MATHEMATICAL LOGIC; ORGANS; OXIDES; OXYGEN COMPOUNDS; TOMOGRAPHY

Optional Information

Notes
36 refs.