Published 2011
| Version v1
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Minimizing Molybdenum 99 contamination in Technetium 99m Pertechnetate from the elution of 99Mo/ 99m Tc Generator
- 1. Malaysian Nuclear Agency, Bangi, Kajang, Selangor (Malaysia), Medical Technology Div.
Description
Radioisotope Tc-99m is widely used for variety of nuclear medicine diagnostic procedures. For many commercial applications, it is prepared in a portable type generator. Nuclear Malaysia has been producing a dry type alumina chromatographic column generator utilizing fission Mo-99. This injectable Tc-99m must meet the British Pharmacopeia [1] product specification prior to be apply on patient. This paper provides a method to minimize the up to acceptable level Mo-99 in the final product. Purposely made pertechnetate contaminated with Mo-99 and re-eluate by using old generator. Excellent removal of Mo-99 impurity was achieved and more than 80 % of Tc-99m total activity was recovered. (author)
Availability note (English)
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44122606.pdf
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Additional details
Publishing Information
- Imprint Pagination
- 8 p.
- Report number
- INIS-MY--2013-081
Conference
- Title
- Nuclear Technical Convention 2011
- Acronym
- NTC 2011
- Dates
- 13-15 Sep 2011
- Place
- Bangi (Malaysia)
INIS
- Country of Publication
- Malaysia
- Country of Input or Organization
- Malaysia
- INIS RN
- 44122606
- Subject category
- ISOTOPES AND RADIATION SOURCES; RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference
- Quality check status
- Yes
- Descriptors DEI
- DIAGNOSTIC USES; EXTRACTION COLUMNS; IMPURITIES; MOLYBDENUM 99; RADIOISOTOPE GENERATORS; REMOVAL; TECHNETIUM 99;
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; EQUIPMENT; EVEN-ODD NUCLEI; EXTRACTION APPARATUSES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MOLYBDENUM ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; RADIOISOTOPES; SEPARATION EQUIPMENT; TECHNETIUM ISOTOPES; USES; YEARS LIVING RADIOISOTOPES;
Optional Information
- Notes
- Oral presentation