Published 2011 | Version v1
Miscellaneous Open

Minimizing Molybdenum 99 contamination in Technetium 99m Pertechnetate from the elution of 99Mo/ 99m Tc Generator

  • 1. Malaysian Nuclear Agency, Bangi, Kajang, Selangor (Malaysia), Medical Technology Div.

Description

Radioisotope Tc-99m is widely used for variety of nuclear medicine diagnostic procedures. For many commercial applications, it is prepared in a portable type generator. Nuclear Malaysia has been producing a dry type alumina chromatographic column generator utilizing fission Mo-99. This injectable Tc-99m must meet the British Pharmacopeia [1] product specification prior to be apply on patient. This paper provides a method to minimize the up to acceptable level Mo-99 in the final product. Purposely made pertechnetate contaminated with Mo-99 and re-eluate by using old generator. Excellent removal of Mo-99 impurity was achieved and more than 80 % of Tc-99m total activity was recovered. (author)

Availability note (English)

Also available in Malaysian Nuclear Agency Document Delivery Center

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Additional details

Publishing Information

Imprint Pagination
8 p.
Report number
INIS-MY--2013-081

Conference

Title
Nuclear Technical Convention 2011
Acronym
NTC 2011
Dates
13-15 Sep 2011
Place
Bangi (Malaysia)

Optional Information

Notes
Oral presentation