Published July 1993 | Version v1
Journal article Metadata-only

Radiosensitizing effect of hyperthermia in stem cells of mouse spermatogenic epithelium

Creators

  • 1. Akademiya Meditsinskikh Nauk SSSR, Obninsk (Russian Federation). Nauchno-Issledovatel'skij Inst. Meditsinskoj Radiologii

Description

Mouse testes preheated up to 41,5 degC for 30 min exibit an increased radiosensitivity of testis epithelium stem cells. High death rate is described by a shift (by ∼ 4 Gy) in the 'dose-response' curve to the Abscissa left. The DMF value for hyperthermia depends on the cell survival rate, at which calculations are made, and varies from 2.1 to 1.4 within the range under study. 5 refs., 1 fig

Additional details

Additional titles

Original title (Russian)
Радиосенсибилизирующий эффект гипертермии (41,5 градс, 30 мин) для стволовых клеток сперматогенного эпителия мышей

Publishing Information

Journal Title
Radiatsionnaya Biologiya, Radioehkologiya
Journal Volume
33
Journal Issue
1
Journal Page Range
p. 564-566.
CODEN
RBIREJ

INIS

Country of Publication
Russian Federation
Country of Input or Organization
Russian Federation
INIS RN
25033640
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
DOSE-RESPONSE RELATIONSHIPS; EPITHELIUM; HYPERTHERMIA; MICE; RADIOSENSITIVITY; STEM CELLS; SURVIVAL CURVES; TESTES
Descriptors DEC
ANIMAL CELLS; ANIMALS; BODY; BODY TEMPERATURE; GONADS; MALE GENITALS; MAMMALS; ORGANS; RODENTS; SOMATIC CELLS; TISSUES; VERTEBRATES