CT scan findings and EEG in systemic lupus erythematodes patients with neuro-psychiatric disorders

In 14 patients with systemic lupus erythematodes presenting with neuro-psychiatric disorders, CT scans were compared with encephalographic (EEG) findings. CT findings were markedly abnormal in 6, slight with a sulcal enlargement in 3, and normal in 5. In the group of markedly abnormal CT findings, focal abnormal low density areas were detected in 2, severe generalized cerebral atrophy in one, and severe atrophy of the right hemisphere in one. EEG findings included focal paroxysmal abnormality of high voltage slow burst at the left frontal dominance and positive spike on the right hemisphere. Epileptic seizure and depressed sensorium seemed to be related to CT abnormality. In 3 patients with epileptic seizures, their symptoms were closely related to CT abnormality. Parkinsonisms and depressed sensorium were also related to CT abnormality. (Namekawa, K)