Published October 4, 1975 | Version v1
Journal article Metadata-only

Acute changes in thyroid function in patients treated with radioactive iodine

Creators

  • 1. Veterans Administration Hospital, Minneapolis, Minn. (USA)

Description

Serum triiodothyronine (T3) and thyroxine (T4) were measured in thirteen unselected hyperthyroid patients before and at frequent intervals after iodine-131 treatment. There was an abrupt rise in T3 from a pretreatment mean of 250ng/100ml to a maximum of 365ng/100ml at 24 hours. Total T4 rose from a mean of 18.7μg/100ml to a maximum of 22.3μg/100ml at 24 to 48 hours. These findings may explain why an occasional patient develops acute thyroid crisis after radioiodine treatment. (author)

Additional details

Identifiers

DOI
10.1016/s0140-6736(75)90117-8;

Publishing Information

Journal Title
The Lancet
Journal Volume
306
Journal Issue
7936
Series
Lancet.
Journal Page Range
635-637
ISSN
0140-6736

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
7223649
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOCHEMISTRY; BIOLOGICAL RADIATION EFFECTS; BLOOD SERUM; IODINE 131; NUCLEAR MEDICINE; PATIENTS; QUANTITY RATIO; RADIOPHARMACEUTICALS; RADIOTHERAPY; SIDE EFFECTS; THYROID; THYROID HORMONES; THYROXINE; TIME DEPENDENCE; TRIIODOTHYRONINE
Descriptors DEC
AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BODY; CARBOXYLIC ACIDS; CHEMISTRY; DAYS LIVING RADIOISOTOPES; DRUGS; ENDOCRINE GLANDS; GLANDS; HORMONES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANS; PEPTIDE HORMONES; RADIATION EFFECTS; RADIOACTIVE MATERIALS; RADIOISOTOPES; THERAPY

Optional Information

Notes
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