Published July 2018 | Version v1
Journal article Metadata-only

Monte Carlo study of dose distribution improvement by skin-shielding layer design in boron neutron capture therapy for non-small-cell lung cancer

Creators

  • 1. Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Nanjing 210016, P.R. (China)
  • 2. Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, P.R. (China)

Description

The skin dose exceeds its dose limitation easily in using an accelerator-based neutron source for non-small-cell lung cancer (NSCLC) with boron neutron capture therapy (BNCT). To solve this problem, design analyses in materials and thicknesses of skin-shielding schemes were investigated through Monte Carlo method. Two skin-shielding schemes were better and could reduce the healthy organ dose: scheme A (0.1 cm-thick thermoplastic with 96%-enriched 6LiF), and scheme B (0.6 cm-thick lithium carbonate). Scheme B with shorter irradiation time was the optimized schemes to improve the dose distribution of BNCT for NSCLC. (authors)

Availability note (English)

Available from doi: http://dx.doi.org/10.1051/radiopro/2018024

Additional details

Identifiers

DOI
10.1051/radiopro/2018024;

Publishing Information

Journal Title
Radioprotection
Journal Volume
53
Journal Issue
no.3
Journal Page Range
p. 207-217
ISSN
0033-8451

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
52098710
Subject category
S61: RADIATION PROTECTION AND DOSIMETRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ACCELERATORS; BORON; DESIGN; IRRADIATION; LITHIUM CARBONATES; LITHIUM FLUORIDES; MONTE CARLO METHOD; NEOPLASMS; NEUTRON CAPTURE THERAPY; NEUTRON SOURCES; RADIATION DOSE DISTRIBUTIONS; RADIATION HAZARDS; RADIATION PROTECTION; SHIELDING; THERAPEUTIC DOSES; THERMOPLASTICS; THICKNESS
Descriptors DEC
ALKALI METAL COMPOUNDS; CALCULATION METHODS; CARBON COMPOUNDS; CARBONATES; DIMENSIONS; DISEASES; DOSES; ELEMENTS; FLUORIDES; FLUORINE COMPOUNDS; HALIDES; HALOGEN COMPOUNDS; HAZARDS; HEALTH HAZARDS; LITHIUM COMPOUNDS; LITHIUM HALIDES; MATERIALS; MEDICINE; NEUTRON THERAPY; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANIC POLYMERS; OXYGEN COMPOUNDS; PARTICLE SOURCES; PETROCHEMICALS; PETROLEUM PRODUCTS; PLASTICS; POLYMERS; RADIATION SOURCES; RADIOLOGY; RADIOTHERAPY; SEMIMETALS; SYNTHETIC MATERIALS; THERAPY

Optional Information

Notes
27 refs.