Published November 2005
| Version v1
Journal article
Cyclooxygenase and radiation-induced gastrointestinal injury
Creators
- 1. State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Combined Injury, College of Preventive Medicine, Third Military Medical Univ., Chongqing (China)
Description
Prostaglandins is a family of eicosanoids, which have many biological functions. Cyclooxygenase is the key enzyme of the prostaglandins' biosynthesis and is has two isoforms: COX-1 and COX-2. Many researchs indicate that prostaglandins and cyclooxygenase play positive protective role in gastrointestinal tract. In this review, the role of prostaglandins and cyclooxygenase in radiation-induced gastrointestinal injury, as well aas their biochemistry and physiology is summarized. (authors)
Additional details
Publishing Information
- Journal Title
- Foreign Medical Sciences. Section of Radiation Medicine and Nuclear Medicine
- Journal Volume
- 29
- Journal Issue
- 6
- Journal Page Range
- p. 278-281
- ISSN
- 1001-098X
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 37119491
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOCHEMISTRY; BIOLOGICAL FUNCTIONS; BIOSYNTHESIS; ENZYMES; GASTROINTESTINAL TRACT; PHYSIOLOGY; PROSTAGLANDINS; RADIATION INJURIES; RADIATION PROTECTION; RADIOPROTECTIVE SUBSTANCES
- Descriptors DEC
- BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; CHEMISTRY; DIGESTIVE SYSTEM; DISEASES; DRUGS; INJURIES; ORGANIC COMPOUNDS; PROTEINS; RADIATION EFFECTS; RESPONSE MODIFYING FACTORS; SYNTHESIS
Optional Information
- Notes
- 14 refs.