The French experience of PSMA PET for the diagnosis of biological recurrence of prostate cancer
Creators
- 1. Centre Leon-Berard, medecine nucleaire, service LUMEN, 15, rue Gabriel-Sarrazin 69008 Lyon (France)
- 2. Hospices civils de Lyon, service LUMEN, 15, rue Gabriel-Sarrazin 69008 Lyon (France)
Description
PSMA PET can only be performed in France in the context of a temporary authorization for use (ATU) granted by the ANSM only in the event of biological recurrence of prostate cancers with a normal or equivocal Fucyclovine or Choline PET scan. We present the experience of the Leon Berard cancer centre and report on the experience of 3 other French centres that have published their results obtained within the framework of this ATU. Despite the absence of histological comparison of our results, the evidence of suspicious lesions on PSMA PET examination may induce changes in patient management in almost 2/3 of the patients. This is consistent with the already abundant results in the literature, which show a clear superiority of PSMA PET over Choline PET for the diagnosis of biological recurrence of prostate cancer (authors)
Availability note (English)
Available from doi: http://dx.doi.org/10.1016/j.mednuc.2019.04.004Abstract (French)
La TEP au PSMA ne peut etre realisee en France que dans le contexte d'une autorisation temporaire d'utilisation (ATU) accordee par l'ANSM uniquement en cas de recidive biologique des cancers de prostate avec une TEP Choline ou TEP a la Fucyclovine normale ou non contributive car equivoque. Nous presentons l'experience du centre Leon Berard et rapportons celle de 3 autres centres Francais ayant publie leurs resultats obtenus dans le cadre de cette ATU. Malgre l'absence de confrontation histologique de nos resultats, la mise en evidence de foyers d'allure suspecte beaucoup plus nombreux sur l'examen TEP PSMA peut induire des modifications de prise en charge pour pres des 2/3 des patients. Cela est en concordance avec les resultats deja abondants de la litterature qui montrent une franche superiorite de la TEP PSMA sur la TEP choline pour le diagnostic de recidive biologique des cancers de prostate. (auteurs)Additional details
Additional titles
- Original title (English)
- L'experience Francaise de la TEP PSMA pour le diagnostic de recidive biologique des cancers de prostate
Identifiers
Publishing Information
- Journal Title
- Medecine Nucleaire. Imagerie Fonctionnelle et Metabolique
- Journal Volume
- 43
- Journal Issue
- no.3
- Journal Page Range
- p. 295-297
- ISSN
- 0928-1258
- CODEN
- MNIMEX
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 53087629
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CHOLINE; DIAGNOSIS; NEOPLASMS; PATIENTS; POSITRON COMPUTED TOMOGRAPHY; PROSTATE
- Descriptors DEC
- ALCOHOLS; AMMONIUM COMPOUNDS; BODY; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; GLANDS; HYDROXY COMPOUNDS; LIPOTROPIC FACTORS; MALE GENITALS; ORGANIC COMPOUNDS; ORGANS; QUATERNARY AMMONIUM COMPOUNDS; TOMOGRAPHY
Optional Information
- Notes
- 7 refs.