Published November 1986 | Version v1
Journal article Metadata-only

Phasic changes in permeability of the blood-brain barrier after selective γ-irradiation of mice

Creators

  • 1. Institute of Biophysics, Moscow, USSR

Description

The aim of this investigation was to determine early changes in permeability of the blood-brain barrier (BBB) in mice after irradiation of the head or trunk. Unilateral irradiation with 60Co gamma-quanta, with a dose rate of 1.43 mA/kg on the midline of the animal's body was given. The results show that permeability of BBB was increased immediately after irradiation. A study of correlation between BBB permeability and the frequency of appearance of neurological symptoms which was determined in parallel experiments is shown

Additional details

Publishing Information

Journal Title
Bull. Exp. Biol. Med. (Engl. Transl.)
Journal Volume
101
Journal Issue
6
Series
Bull. Exp. Biol. Med. (Engl. Transl.).
Journal Page Range
777-779
ISSN
0007-4888
CODEN
BEXBA

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
19040509
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Translation
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; BLOOD-BRAIN BARRIER; COBALT 60; DOSE-RESPONSE RELATIONSHIPS; GAMMA RADIATION; HEAD; MICE; NERVOUS SYSTEM DISEASES; NEUROLOGY; PARTIAL BODY IRRADIATION; PERMEABILITY; RADIATION DOSES; SYMPTOMS
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BODY; BODY AREAS; COBALT ISOTOPES; DISEASES; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MEDICINE; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RODENTS; VERTEBRATES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
Translated from Byulleten' Ehksperimental'noj Biologii i Meditsiny; 101: No. 6, 697-699(Jun 1986).