Handbook of tritium NMR spectroscopy and applications

Following a brief introduction, highlighting the importance of 3H nmr spectroscopy for tritium tracer studies, Chapter 1 deals with the theory of the method, the interpretation of spectra and other experimental aspects, emphasizing the importance of careful sample preparation and the special relationship of 3H nmr spectral detail to the wealth of published data for proton spectra. Chapter 2 reviews the current methods for labelling compounds with tritium and the relationship of observed patterns of labelling to these methods. Chapter 3 describes applications of 3H nmr spectroscopy to research in the life sciences which illustrate the power of the technique. Studies employing this analytical tool have revealed numerous interesting and indeed unexpected results in the behaviour of tritium atoms in labelled molecules. These studies have included applications of tritiated compounds in analytical and biochemical problems, in problems of catalysis and reaction mechanisms, and in other areas of scientific research. (author)