Published June 20, 1989 | Version v1
Journal article Metadata-only

Changes in the intrinsic fluorescence of lymphocytes after irradiation

Creators

  • 1. Research Institute of Preventive Medicine, Bratislava (Czechoslovakia)

Description

The changes in the intrinsic fluorescence of peripheral lymphocyte membranes after irradiation in vivo were investigated. The linear increase of fluorescence after irradiation with gamma field of 60Co and/or neutrons of 252Cf sources was found. The value of RBE of neutrons for this biological effect was found to be 3.7. The decrease of fluorescence polarization with increasing dose of both gamma and neutron irradiation was interpreted as due to structural changes of immediate vicinity of tryptophan molecules and thus conformational changes of lymphocyte membrane proteins. (author)

Additional details

Publishing Information

Journal Title
Studia Biophysica
Journal Volume
131
Journal Issue
1-2
Series
Stud. Biophys.
Journal Page Range
67-73
ISSN
0081-6337
CODEN
STBIB

INIS

Country of Publication
Germany
Country of Input or Organization
German Democratic Republic
INIS RN
20084386
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CALIFORNIUM 252; CELL MEMBRANES; COBALT 60; FLUORESCENCE; GAMMA RADIATION; LYMPHOCYTES; NEUTRON BEAMS; RATS; RBE
Descriptors DEC
ACTINIDE NUCLEI; ALPHA DECAY RADIOISOTOPES; ANIMAL CELLS; ANIMALS; BEAMS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CALIFORNIUM ISOTOPES; CELL CONSTITUENTS; COBALT ISOTOPES; CONNECTIVE TISSUE CELLS; ELECTROMAGNETIC RADIATION; EMISSION; EVEN-EVEN NUCLEI; HEAVY NUCLEI; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LEUKOCYTES; LUMINESCENCE; MAMMALS; MATERIALS; MEMBRANES; MINUTES LIVING RADIOISOTOPES; NUCLEI; NUCLEON BEAMS; ODD-ODD NUCLEI; PARTICLE BEAMS; PHOTON EMISSION; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RODENTS; SOMATIC CELLS; SPONTANEOUS FISSION RADIOISOTO; VERTEBRATES; YEARS LIVING RADIOISOTOPES