Published April 1979
| Version v1
Journal article
Effect of photoreactivating light on lethal and pre-mutational UV lesions in Escherichia coli WP2, carrying the R46 mutator plasmid
Description
an excision-deficient E. coli strain carrying the R46 mutator plasmid showed a different reponse towards photo-reactivation after UV irradiation than the same strain without plasmid. While the photoreactivation of lethal lesions was comparable is both strains, the number of UV-induced mutants per 106 survivors was slightly reduced for the plasmid bearing strain by photoreactivating light at UV fluences below 60mJ/m2 but increased at higher fluences. To explain this it is proposed that some UV photoproduct(s) of DNA other than cyclobutane dipyrimidine dimers are pre-mutational lesions for error-prone DNA repair by the plasmid, P-repair, but not for SOS-repair. (Author)
Additional details
Publishing Information
- Journal Title
- Photochem. Photobiol.
- Journal Volume
- 29
- Journal Issue
- 4
- Series
- Photochem. Photobiol.
- Journal Page Range
- 781-784
- ISSN
- 0031-8655
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 10472935
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; CELL CONSTITUENTS; CHEMICAL RADIATION EFFECTS; DNA; ESCHERICHIA COLI; EXPERIMENTAL DATA; GRAPHS; LETHAL IRRADIATION; MUTAGENESIS; MUTANTS; PHOTOREACTIVATION; SURVIVAL CURVES; ULTRAVIOLET RADIATION
- Descriptors DEC
- BACTERIA; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; DATA; DATA FORMS; ELECTROMAGNETIC RADIATION; INFORMATION; IRRADIATION; MICROORGANISMS; NUCLEIC ACIDS; NUMERICAL DATA; ORGANIC COMPOUNDS; RADIATION EFFECTS; RADIATIONS