Published April 1978 | Version v1
Journal article Metadata-only

Chemical form of the radioactive excretion products after intravenous application of 125I-orthoiodohippurate to rats

Creators

  • 1. Bundesgesundheitsamt, Berlin (Germany, F.R.). Inst. fuer Strahlenhygiene

Description

100 μCi 125I-orthoiodohippurate were injected i.v. to 2 Wistar rats. Urine and faeces were analysed by means of thin-layer chromatography and high-pressure liquid chromatography. The metabolites found were 125I-orthoiodobenzoic acid, 125I-orthoiodohippuric acid, and 125I-iodide. (orig./MG)

Abstract (German)

Zwei Wistar-Ratten wurden je 100 μCi125J-Orthojodhippuran i. v. verabreicht. Urin und Faeces wurden mit Hilfe der Dünnschichtchromatographie und der Hochdruckflüssigkeitschromatographie analysiert. Die zusammenfassende Stoffwechselbilanz ergab folgendes Resultat : Ratte 1: 15% 125J-Orthojodbenzoesäure, 66% 125J-Orthojodhippursäure und 12,5% 125J-Jodid. Ratte 2: 18,5% 125J-Orthojodbenzoesäure, 67,5% 125J-Orthojodhippursäure und 10,2% 125J-Jodid.

Additional details

Additional titles

Original title (German)
Chemische Form der radioaktiven Ausscheidungsprodukte nach intravenoeser Verabreichung von

Identifiers

DOI
10.1055/s-0037-1620669;

Publishing Information

Journal Title
Nuklearmedizin
Journal Volume
17
Journal Issue
02
Series
Nucl.-Med.
Journal Page Range
53-56
ISSN
0029-5566

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
9417856
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
BENZOIC ACID; EXCRETION; FECES; HIPPURAN; HIPPURIC ACID; INTRAVENOUS INJECTION; IODIDES; IODINE 125; METABOLISM; METABOLITES; ORGANIC IODINE COMPOUNDS; QUALITATIVE CHEMICAL ANALYSIS; RADIOPHARMACEUTICALS; RATS; THIN-LAYER CHROMATOGRAPHY; URINE
Descriptors DEC
AMINO ACIDS; ANIMALS; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BODY FLUIDS; CARBOXYLIC ACIDS; CHEMICAL ANALYSIS; CHROMATOGRAPHY; CLEARANCE; CONTRAST MEDIA; DAYS LIVING RADIOISOTOPES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; HALIDES; HALOGEN COMPOUNDS; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; IODINE COMPOUNDS; IODINE ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MONOCARBOXYLIC ACIDS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; SEPARATION PROCESSES; VERTEBRATES; WASTES

Optional Information

Notes
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