Published January 2002
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Autoradiographic evaluation of novel high-affinity 99mTc- radioligands for the 5-HT1A receptor (II)
Description
The regional in vitro distribution in rat brain sections of two 99mTcO(V) ''3+1'' mixed-ligand complexes derived from WAY 100635 and desmethyl WAY (DWAY) resp. were compared. The DWAY-derived complex 99mTc 7 showed a higher selectivity for the 5-HT1A receptor than the WAY-derivative 99mTc 5. (orig.)
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Additional details
Publishing Information
- Imprint Title
- Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 2001
- Imprint Pagination
- 113 p.
- Journal Page Range
- p. 32
- ISSN
- 1437-322X
- Report number
- FZR--340
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 35062609
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- AFFINITY; AUTORADIOGRAPHY; BRAIN; COMPARATIVE EVALUATIONS; IN VITRO; LABELLED COMPOUNDS; LIGANDS; RATS; RECEPTORS; TECHNETIUM 99; TECHNETIUM COMPLEXES; TISSUE DISTRIBUTION; TRACER TECHNIQUES
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CENTRAL NERVOUS SYSTEM; COMPLEXES; DISTRIBUTION; EVALUATION; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MEMBRANE PROTEINS; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIOISOTOPES; RODENTS; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPLEXES; VERTEBRATES; YEARS LIVING RADIOISOTOPES