A survey on quantitative analysis of organic compounds by nuclear magnetic resonance (NMR) spectroscopy

Nuclear Magnetic Resonance (NMR) spectroscopy is known as a powerful analytical technique, which is used to determine the structure of small and macro organic compounds. In recent years, ¹H NMR is being recognized more and more as a quantitative analytical method, which is based on the principle where the area under a ¹H NMR signal peak in solution state is proportional to the number of nuclei contributing to the peak. In this report, the basic concepts, developmental history and current state of the quantitative ¹H NMR (qNMR) method are described. Furthermore, future prospect of the qNMR method is presented. (author)