Determination of folic acid via its quenching effect on the fluorescence of MoS2 quantum dots
Creators
- 1. Ningxia University, State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering, National Demonstration Center for Experimental Chemistry Education, College of Chemistry and Chemical Engineering (China)
Description
Molybdenum disulfide quantum dots (MoS2 QDs) are used in a fluorometric method for the determination of folic acid (FA) based on fluorescence quenching. The MoS2 QDs synthesized by a hydrothermal method possess bright blue fluorescence (with excitation/emission maxima of 325/415 nm), quantum yield of 3.7%, and excellent storage stability in solution (30 days in the refrigerator). Their fluorescence is quenched by FA, and intensity decreases linearly in the 0.1 to 125 μM FA concentration range. The detection limit is 0.1 μM (at S/N = 3), and the relative standard deviation (for n = 5) is 2.8% for 25 μM concentrations of FA. Studies on the quenching mechanism suggest that the effect is due to static quenching. The FA in commercial FA tablets was successfully determined.
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Additional details
Identifiers
Publishing Information
- Journal Title
- Mikrochimica Acta
- Journal Volume
- 186
- Journal Issue
- 9
- Journal Page Range
- p. 1-8
- ISSN
- 0026-3672
- CODEN
- MIACAQ
INIS
- Country of Publication
- Austria
- Country of Input or Organization
- Austria
- INIS RN
- 52068493
- Subject category
- S77: NANOSCIENCE AND NANOTECHNOLOGY; S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Descriptors DEI
- CHEMICAL PREPARATION; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; FOLIC ACID; HYDROTHERMAL SYNTHESIS; MOLYBDENUM SULFIDES; NANOCHEMISTRY; QUANTUM DOTS
- Descriptors DEC
- AMINO ACIDS; AROMATICS; AZAARENES; CARBOXYLIC ACIDS; CHALCOGENIDES; CHEMISTRY; DRUGS; EMISSION; EMISSION SPECTROSCOPY; HEMATINICS; HEMATOLOGIC AGENTS; HETEROCYCLIC COMPOUNDS; HYDROCARBONS; HYDROXY COMPOUNDS; LUMINESCENCE; MOLYBDENUM COMPOUNDS; NANOSTRUCTURES; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PHOTON EMISSION; PTERIDINES; REFRACTORY METAL COMPOUNDS; SPECTROSCOPY; SULFIDES; SULFUR COMPOUNDS; SYNTHESIS; TRANSITION ELEMENT COMPOUNDS; VITAMIN B GROUP; VITAMINS
Optional Information
- Copyright
- Copyright (c) 2019 Springer-Verlag GmbH Austria, part of Springer Nature