Published April 1992 | Version v1
Journal article

Kinetics of isotope exchange between [3-(iodophenyl)methyl]guanidine (mIBG) and [131I]-iodide

  • 1. Institut za Nuklearne Nauke Boris Kidric, Belgrade (Yugoslavia)
  • 2. Belgrade Univ. (Yugoslavia)

Description

The reaction of isotope exchange betweeen [3-(iodophenyl)methyl]guanidine, mIBG, and [131I]-iodide in relatively concentrated solutions, in the presence of different ammonium salts, in a closed system, over the temperature range from 130 to 150 C deg, has been investigated. The reaction occurs either with (NH4)2SO4 or CH3COOH, which indicates that the reaction goes through some intermediate stages. Kinetic studies show the influence of the additives. The activation energies for the reaction with (NH4)2SO4/H2O, (NH4)2SO4/CH3COOH and CH3COOH are 121.1, 115.1 and 84.5 kJ * mol-1, respectively. (author) 15 refs.; 5 figs.; 1 tab

Additional details

Publishing Information

Journal Title
Journal of Radioanalytical and Nuclear Chemistry
Journal Volume
158
Journal Issue
1
Series
Articles.
Journal Page Range
p. 183-191.
ISSN
0236-5731
CODEN
JRNCDM