Published 2005
| Version v1
Miscellaneous
Carbon-14 labeling of drug candidates
- 1. SRI International, Menlo Park (United States)
- 2. Korea Institute of Bioscience and Biotechnology, Taejon (Korea, Republic of)
- 3. Dong-Kook Pharmaceutical Co., Ltd., Seoul (Korea, Republic of)
Description
Utilizing the 'degradation and reconstruction method,' Carbon-14 labeling of two biologically active compounds were prepared: a new pimaradiene type (acanthoic acid), (-)-pimara-9(11), 15-diene-19-oic acid (A-1), a morphine analogue DK-1001 (6,14-endo-ethano-7-(2-hydroxy-2-cyclopropyl-2-methyl) tetrahydrooripavine(B-1)
Additional details
Publishing Information
- Publisher
- KAERI
- Imprint Place
- Taejon (Korea, Republic of)
- Imprint Title
- Proceedings of international symposium on research reactor and neutron science
- Imprint Pagination
- 922 p.
- Journal Page Range
- p. 95-98
Conference
- Title
- International symposium on research reactor and neutron science
- Dates
- 11-13 Apr 2005
- Place
- Taejon (Korea, Republic of)
INIS
- Country of Publication
- Korea, Republic of
- Country of Input or Organization
- Korea, Republic of
- INIS RN
- 37008044
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Conference, Non-conventional Literature
- Descriptors DEI
- CARBON 14; DRUGS; LABELLING; METHYLATION; RADIOISOTOPES
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBON ISOTOPES; CHEMICAL REACTIONS; EVEN-EVEN NUCLEI; ISOTOPES; LIGHT NUCLEI; NUCLEI; RADIOISOTOPES; YEARS LIVING RADIOISOTOPES
Optional Information
- Notes
- 6 refs