Published 1989
| Version v1
Book
Radiation sensitizers and bioreductive drugs
Description
This paper presents the development of methods that lead to an increase in the radiosensitivity of hypoxic cells in tumors. Focus is on the use of electron affinic radiosensitizers and one of these, misonidazole, that has undergone extensive clinical trial. Benefits and limitations of this compound are addressed. Clinical experience in relation to the oxygen effect is considered
Additional details
Publishing Information
- Publisher
- Elsevier Science Pub. Co., Inc.
- Imprint Place
- New York, NY (USA)
- ISBN
- 0-444-81099-4
- Imprint Title
- The biological basis of radiotherapy. Second edition
- Imprint Pagination
- 322 p.
- Journal Page Range
- p. 145-162.
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 21087404
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S61: RADIATION PROTECTION AND DOSIMETRY;
- Descriptors DEI
- ANEMIAS; ANOXIA; ANTINEOPLASTIC DRUGS; CARCINOMAS; CHEMICAL REACTION KINETICS; DATA PROCESSING; MISONIDAZOLE; OXYGEN; RADIOSENSITIVITY; RADIOTHERAPY; RESEARCH PROGRAMS; RESPONSE MODIFYING FACTORS; TOXICITY; TUMOR CELLS; UTERUS
- Descriptors DEC
- ALCOHOLS; ANIMAL CELLS; AZOLES; BODY; DISEASES; DRUGS; ELEMENTS; FEMALE GENITALS; HEMIC DISEASES; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; IMIDAZOLES; KINETICS; MEDICINE; NEOPLASMS; NITRO COMPOUNDS; NONMETALS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; RADIOSENSITIZERS; REACTION KINETICS; SYMPTOMS; THERAPY