Influence of radiation on microcirculation of mouse kidney and its treatment
Description
The changes in microcirculation of kidney were observed in mice irradiated and subsequently treated. After irradiation with 15 Gy of γ-ray, the decrease of renal capillary beds and vessel calibre, increase in number of leukocytes, aggregation of erythrocytes, and appearance of white microthrombi in capillaries were found. These changes disturbed seriously the exchange of substances between the tissues and cells, and sometimes they could lead to the death of mice. By treatment with some drugs, these changes were mitigated and the survival rate of animal was raised. It is suggested that the improvement of renal microcirculation by combined treatment of Chinese traditional medicine and western medicine is an effective way to correct the functional disturbance of kidney and to treat acute radiation sickness
Additional details
Publishing Information
- Journal Title
- Chin. J. Radiol. Med. Prot.
- Journal Volume
- 4
- Journal Issue
- 6
- Series
- Chin. J. Radiol. Med. Prot.
- Journal Page Range
- 19-21
- CODEN
- ZFYZD
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 17039352
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; CAPILLARIES; COBALT 60; GAMMA RADIATION; KIDNEYS; MICE; MORPHOLOGICAL CHANGES; THERAPY
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BLOOD VESSELS; BODY; CARDIOVASCULAR SYSTEM; COBALT ISOTOPES; ELECTROMAGNETIC RADIATION; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MEDICINE; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RODENTS; VERTEBRATES; YEARS LIVING RADIOISOTOPES