Published July 2018 | Version v1
Journal article

Positive and bounded nonstandard finite difference scheme for the Hodgkin–Huxley equations

  • 1. Obafemi Awolowo University, Department of Mathematics (Nigeria)
  • 2. University of Pretoria, Department of Mathematics and Applied Mathematics (South Africa)

Description

In this work we consider the Hodgkin Huxley model in the form of a coupled system of one singularly perturbed partial differential equation and three ordinary differential equations. The existence of a small parameter, the nonlinearity and the coupling makes the numerical approximations using explicit finite difference schemes very difficult. In particular, spurious oscillations have been observed to exist. Here we propose the use of nonstandard finite difference to improve on the existing time step restrictions. In addition, we prove that the proposed scheme preserves positivity and is elementary stable. Numerical simulations will be given to support the performance of the proposed scheme.

Additional details

Identifiers

Publishing Information

Journal Title
Japan Journal of Industrial and Applied Mathematics (Internet)
Journal Volume
35
Journal Issue
2
Journal Page Range
p. 773-785
ISSN
1868-937X

INIS

Country of Publication
Japan
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
50057663
Subject category
S97: MATHEMATICAL METHODS AND COMPUTING;
Descriptors DEI
APPROXIMATIONS; COMPUTERIZED SIMULATION; PARTIAL DIFFERENTIAL EQUATIONS
Descriptors DEC
CALCULATION METHODS; DIFFERENTIAL EQUATIONS; EQUATIONS; SIMULATION

Optional Information

Copyright
Copyright (c) 2018 The JJIAM Publishing Committee and Springer Japan KK, part of Springer Nature