Published December 1981 | Version v1
Journal article Metadata-only

Bilateral internuclear ophthalmoplegia after intrathecal chemotherapy and cranial irradiation

Creators

  • 1. Department of Neurology, College of Medicine and Dentistry of New Jersey, Rutgers Medical School, Piscataway

Description

A 26-year-old man developed transient bilateral internuclear ophthalmoplegia with exotropia after cranial irradiation and intrathecal administration of methotrexate for lymphoma. Resolution of the ophthalmoplegia and the decrease in abnormally high levels of cerebrospinal fluid myelin basic protein after discontinuation of intrathecal medication suggested demyelination from chemotherapy and irradiation

Additional details

Publishing Information

Journal Title
Am. J. Ophthalmol.
Journal Volume
92
Journal Issue
6
Series
Am. J. Ophthalmol.
Journal Page Range
851-853
ISSN
0002-9394

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
13702511
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S62: RADIOLOGY AND NUCLEAR MEDICINE; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
CEREBROSPINAL FLUID; CHEMOTHERAPY; EYES; HEAD; LYMPHOMAS; METHOTREXATE; MYELIN; PATIENTS; PROTEINS; RADIATION EFFECTS; RADIOTHERAPY; SENSE ORGANS DISEASES; SIDE EFFECTS
Descriptors DEC
ANTIMETABOLITES; ANTIMITOTIC DRUGS; BIOLOGICAL MATERIALS; BODY; BODY AREAS; BODY FLUIDS; DISEASES; DRUGS; LIPIDS; LIPOPROTEINS; MEDICINE; NEOPLASMS; ORGANIC COMPOUNDS; ORGANS; SENSE ORGANS; THERAPY