Calibration of methanol and ethylene glycol nuclear magnetic resonance thermometers

A guadratic equation describing the difference in temperature of a methanol sample as a function of the separation (in H2) between the OH proton and the CH3 protons, and a linear relationship between temperature and separation of the OH protons and CH2 protons of ethylene glycol performed at 220 MHz were reported. This data demonstrated that Van Geet's 60-MHz calibration equations may be confidently scaled up to 220 MHz, and the agreement suggests that scaling to even higher frequencies should not introduce appreciably larger errors. A Varion HR-220 spectrometer with pulse Fourier transform capability was used. Methanol or glycol was used in an open sample tube for thermocycle measurements. Experimental data was included. The relationship between chemical shift and temperature was reported in calibiaton curve of methanol and glycol at 220 MHz as a function of temperature. 1 table, 1 figure,