Inhalation Toxicology Research Institute: Annual report, October 1, 1985 through September 30, 1986

The first section of this report contains papers related to aerosol generation and characterization. Among the papers in this section, one addresses the evaluation of the particles deposited near the Soviet Chernobyl nuclear reactor accident and provides insight into the nature of the radioactivity released from the reactor and its potential health effects. The second section includes papers describing the deposition and fate of inhaled materials. It contains discussions of the metabolic fate of important chemical and radioactive materials. The third section, dose-response relationships for inhaled radionuclides and the fourth section, dose-response relationships for inhaled chemical toxicants, deal with the health effects from inhaled materials. A number of these papers are updates of life span studies in dogs and in rodents. The final section, biological factors that influence dose-response relationships, contains papers dealing with a broad range of significant biological relationships that need evaluation in order to understand the complex interactions between dose and the produced effects. For those who would like to obtain a quick overview of the Institute's research, a brief summary, highlighting some of the important findings, is at the beginning of each section