Cost effectiveness of silver nanoparticle over gold nanoparticle in nano-particle aided radiotherapy

The prime aim of radiotherapy is to deliver adequate dose to tumor tissue while sparing surrounding normal tissue and the organ at risks. One of the major problems associated with these techniques is the lack of selectivity between the tumor and the surrounding healthy tissue, thus the performance is limited by the tolerance dose of normal tissues and organ at risks. The tumour region can be made radio-sensitive with the infusion of nanoparticles (NPs) which will improve the therapeutic benefit by selectively differentiating tumor and healthy region. The gold NPs are used as radio-sensitizer due to its high atomic number, bio-compatibility and it is well explored for its suitability in dose enhancement. Presently silver NPs are also being explored in radio sensitization like other high Z materials. The cost of silver NPs is almost 10 times less than the gold NPs