Cellular track model for study of heavy ion beams
Description
Track theory is combined with a realistic model of a heavy ion beam to study the effects of nuclear fragmentation on cell survival and biological effectiveness. The effects of secondary reaction products are studied as a function of depth in a water column. Good agreement is found with experimental results for the survival of human T-l cells exposed to monoenergetic carbon, neon, and argon beams under aerobic and hypoxia conditions. The present calculation, which includes the effect of target fragmentation, is a significant improvement over an earlier calculation because of the use of a vastly improved beam model with no change in the track theory or cellular response parameters
Availability note (English)
MF available from INIS under the Report Number; Also available from CASI HC A03/MF A01.
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Additional details
Publishing Information
- Imprint Pagination
- 15 p.
- Report number
- N--94-13714
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 25051902
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- ANIMAL CELLS; BIOLOGICAL RADIATION EFFECTS; HEAVY ION REACTIONS; ION BEAMS; NUCLEAR FRAGMENTATION; RBE
- Descriptors DEC
- BEAMS; BIOLOGICAL EFFECTS; FRAGMENTATION; NUCLEAR REACTIONS; RADIATION EFFECTS
Optional Information
- Contract/Grant/Project number
- RTOP 199-45-16-11
- Secondary number(s)
- NASA-TP--3351; L--17231; NAS--1.60:3351.