Published June 1988 | Version v1
Journal article

Sipple's syndrome with liver tumors examined by iodine-131 MIBG and technetium-99m(V)-DMSA

  • 1. Kyoto Univ. School of Medicine (Japan)

Description

This case report describes the localization and categorization of tumors using /sup 99m/Tc(V)-dimercaptosuccinic acid and [131I]metaiodobenzylguanidine scans in a very uncommon case of medullary thyroid carcinoma associated with pheochromocytoma (Sipple's syndrome) and hepatocellular carcinoma. Technetium-99m(V)-dimercaptosuccinic acid showed accumulation only in medullary thyroid carcinoma, but [131I]metaiodobenzylguanidine scans were positive in both medullary thyroid carcinoma and pheochromocytoma. In advanced Sipple's syndrome, combined use of [/sup 99m/Tc(V)]dimercaptosuccinic acid and [131I]metaiodobenzylguanidine may be useful for the categorization of tumor mass lesions and planning appropriate therapy

Additional details

Publishing Information

Journal Title
J. Nucl. Med.
Journal Volume
29
Journal Issue
6
Series
J. Nucl. Med.
Journal Page Range
1130-1135
ISSN
0022-3123
CODEN
JNMEA