Graphene oxide: an efficient carbocatalyst for the solvent-free synthesis of 2-(substituted benzoyl)-3-(substituted phenyl)imidazo[1,2-a]pyridines

GO has been found as a remarkable heterogeneous carbocatalyst for the solvent-free synthesis of 2-(substituted benzoyl)-3-(substituted phenyl)imidazo[1,2-a]pyridines from chalcones and 2-aminopyridine. The present methodology offers a novel and eco-friendly approach with appreciable yields of the desired products.

Graphic abstract

The properties like low toxicity and recyclability make Graphene Oxide an efficient carbocatalyst for carrying out organic synthesis and reducing the aggravation in an environmental crisis. Therefore, it has been employed successfully for the synthesis of 2-(substituted benzoyl)-3-(substituted phenyl)imidazo[1,2-a]pyridines from chalcones and 2-aminopyridine.