Published March 1979 | Version v1
Journal article Metadata-only

Analysis of mice radiosensitivity depending on age

Creators

  • 1. AN SSSR, Leningrad. Inst. Yadernoj Fiziki

Description

In order to elucidate mechanisms of age variations in radiosensitivity of mice a study was made of the sensitivity of in vitro irradiated bone marrow stem cells, taken from animals of different age, and postradiation recovery of leukocyte content of peripheral blood and cellularity of bone marrow and spleen. Using the method of spleen colonies similar affections were revealed in bone marrow cells of animals of different age. The degree of recovery of the hemopoietic cell pool was significantly lower in newborn mice than in adults after exposure to a dose (LDsub(50/30)) equally effective with respect to mortality

Additional details

Additional titles

Original title (Russian)
К анализу возрастной радиочувствительности мышей

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
19
Journal Issue
2
Series
Radiobiologiya.
Journal Page Range
225-228
ISSN
0033-8192

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
11508208
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Numerical Data
Descriptors DEI
AGE DEPENDENCE; BIOLOGICAL REPAIR; BONE MARROW CELLS; EXPERIMENTAL DATA; GRAPHS; IN VITRO; LETHAL IRRADIATION; LEUKOCYTES; MICE; RADIOSENSITIVITY; SPLEEN; STEM CELLS; TABLES; TIME DEPENDENCE; X RADIATION
Descriptors DEC
ANIMAL CELLS; ANIMALS; BIOLOGICAL MATERIALS; BIOLOGICAL RECOVERY; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DATA; DATA FORMS; ELECTROMAGNETIC RADIATION; INFORMATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; NUMERICAL DATA; ORGANS; RADIATIONS; RODENTS; SOMATIC CELLS; VERTEBRATES

Optional Information

Notes
For English translation see the journal Radiobiology (USA).