Published 1986 | Version v1
Book Metadata-only

Evaluation of human prostate tumors in vivo with P-31 MR spectroscopy

Creators

Description

P-31 MR spectroscopy was performed on the solid human prostate adenocarcinoma PC-3 implanted intramurally into immunodeficient Balb/c nμ/nμ mice. Data were acquired using a 2.35-T magnet and surface coils designed to conform to the tumor. Spectra showed significant (P<.01) correlations of Pi/ATP, PME/ATP, PCr/ATP, and Pi/PCr concentration ratios with tumor volume. Fifteen tumors were irradiated to 20 Gy (n = 7) or 5 Gy (n = 8). After irradiation, significant (P<.05) decreases in pHnmr occurred, along with increases in Pi/ATP. An increase in PCr/ATP occurred 12-24 hours after irradiation, concurrently with renormalization of Pi/ATP. The time course of the changes appeared to be related to dose

Additional details

Publishing Information

Publisher
Radiological Society of North America Inc.
Imprint Place
Oak Brook, IL (USA)
Imprint Title
The 72nd scientific assembly and annual meeting of the Radiological Society of North America (Abstracts)
Journal Page Range
p. 92.

Conference

Title
72. scientific assembly and annual meeting of RSNA.
Dates
30 Nov - 5 Dec 1986.
Place
Chicago, IL (USA).

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
18099642
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CARCINOMAS; DIMENSIONS; DOMAIN STRUCTURE; EVALUATION; GAMMA SPECTROSCOPY; HUMAN POPULATIONS; IN VIVO; NMR IMAGING; NMR SPECTRA; PHOSPHORUS 31; PROSTATE; RADIATION DOSES; TIME DEPENDENCE; UPTAKE
Descriptors DEC
BODY; DIAGNOSTIC TECHNIQUES; DISEASES; GLANDS; ISOTOPES; LIGHT NUCLEI; MALE GENITALS; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; PHOSPHORUS ISOTOPES; POPULATIONS; SPECTRA; SPECTROSCOPY; STABLE ISOTOPES