Published March 1988 | Version v1
Journal article Metadata-only

Acute effects of irradiation on middle ear mucosa

Creators

  • 1. Osaka City Univ. Medical School (Japan)

Description

Single field, fixed irradiation of bilateral tympanic cavities using 200-kV x-rays was administered to five guinea pigs. The irradiation dose was 30 Gy. They were killed immediately after irradiation, and bilateral middle ear mucosa was examined for ciliary activity and epithelial structure. Significant deterioration of the ciliary activity in the middle ear mucosa was observed, proximal as well as distal to the eustachian tube. Electron microscopy showed various changes in the irradiated middle ear mucosa. The most conspicuous findings were hyperreactivity in secretion, vacuolation of ciliated cells, and stomal edema

Additional details

Publishing Information

Journal Title
Ann. Otol., Rhinol., Laryngol.
Journal Volume
97
Series
Ann. Otol., Rhinol., Laryngol.
Journal Page Range
173-178
ISSN
0003-4894
CODEN
AORHA

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
19082703
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
AUDITORY ORGANS; BIOLOGICAL RADIATION EFFECTS; ELECTRON MICROSCOPY; EPITHELIUM; GUINEA PIGS; MUCOUS MEMBRANES; X RADIATION
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BODY; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; MAMMALS; MICROSCOPY; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; SENSE ORGANS; TISSUES; VERTEBRATES