Ultrasound-based radiomics nomogram: A potential biomarker to predict axillary lymph node metastasis in early-stage invasive breast cancer

Highlights: • Radiomics uses features extracted from US images to reflect intratumor heterogeneity. • US-based radiomics score was an independent predictor of ALN metastasis. • A radiomics nomogram outperformed clinical model could facilitate to predict ALN metastasis in patients with EIBC. - Abstract: PurposeTo establish a radiomics nomogram integrating clinical factors and radiomics features from ultrasound for the preoperative diagnosis axillary lymph node (ALN) status in patients with early-stage invasive breast cancer (EIBC).